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Werner Hoffmann Selected Research

Trefoil Factors

11/2021Salivary Trefoil Factor Family (TFF) Peptides and Their Roles in Oral and Esophageal Protection: Therapeutic Potential.
5/2021Trefoil Factor Family (TFF) Peptides and Their Links to Inflammation: A Re-evaluation and New Medical Perspectives.
1/2020Subcellular Localization of the TFF Peptides xP1 and xP4 in the Xenopus laevis Gastric/Esophageal Mucosa: Different Secretion Modes Reflecting Diverse Protective Functions.
11/2019The TFF Peptides xP1 and xP4 Appear in Distinctive Forms in the Xenopus laevis Gastric Mucosa: Indications for Different Protective Functions.
9/2015TFF Peptides Play a Role in the Immune Response Following Oral Infection of Mice with Toxoplasma Gondii.
3/2010Synthesis and localization of trefoil factor family (TFF) peptides in the human urinary tract and TFF2 excretion into the urine.
3/2007Induced trefoil factor family 1 expression by trans-differentiating Clara cells in a murine asthma model.
1/2007TFF (trefoil factor family) peptides and their potential roles for differentiation processes during airway remodeling.
11/2004Epidermal growth factor and trefoil factor family 2 synergistically trigger chemotaxis on BEAS-2B cells via different signaling cascades.
1/2002Cell type specific expression of secretory TFF peptides: colocalization with mucins and synthesis in the brain.

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Werner Hoffmann Research Topics

Disease

4Neoplasms (Cancer)
05/2022 - 01/2002
4Infections
03/2020 - 09/2015
3Complementation Group D Xeroderma Pigmentosum
01/2020 - 01/2002
3Metaplasia
09/2015 - 01/2012
2Asthma (Bronchial Asthma)
03/2007 - 11/2004
1Colitis
02/2022
1Stomatitis
11/2021
1Inflammation (Inflammations)
05/2021
1Carcinogenesis
01/2020
1Toxoplasmosis
06/2017
1Glioblastoma (Glioblastoma Multiforme)
09/2015
1Hyperthermia
09/2015
1Edema (Dropsy)
08/2012
1Nephrolithiasis
03/2010
1Hearing Loss (Hearing Impairment)
01/2008
1Airway Remodeling
01/2007
1Wounds and Injuries (Trauma)
01/2007
1Dry Eye Syndromes (Dry Eye Syndrome)
05/2004
1Gastroesophageal Reflux (GERD)
05/2004
1Lacrimal Apparatus Diseases (Epiphora)
05/2003

Drug/Important Bio-Agent (IBA)

10Trefoil FactorsIBA
11/2021 - 01/2002
5MucinsIBA
03/2020 - 05/2003
3AntralIBA
05/2022 - 01/2020
3LectinsIBA
05/2022 - 11/2019
3spasmolytic polypeptideIBA
09/2015 - 01/2012
2Epidermal Growth Factor (EGF)IBA
01/2007 - 11/2004
1sodium sulfate (sodium bisulfate)FDA LinkGeneric
02/2022
1Dextrans (Dextran)FDA Link
02/2022
1Peptides (Polypeptides)IBA
01/2020
1Reactive Oxygen Species (Oxygen Radicals)IBA
01/2020
1Proteins (Proteins, Gene)FDA Link
01/2020
1EpitopesIBA
11/2019
1SugarsIBA
11/2019
1InflammasomesIBA
06/2017
1Pattern Recognition ReceptorsIBA
06/2017
1SiliconesIBA
08/2012
1Biomarkers (Surrogate Marker)IBA
03/2010
1Trefoil Factor-3IBA
01/2008
1AntigensIBA
03/2007
1Phenobarbital (Luminal)FDA Link
11/2004
1Lubricant Eye Drops (Artificial Tears)IBA
05/2004
1Interleukin-8 (Interleukin 8)IBA
05/2004
1Messenger RNA (mRNA)IBA
05/2003

Therapy/Procedure

1Radiotherapy
11/2021
1Drug Therapy (Chemotherapy)
11/2021
1Combined Modality Therapy
09/2015
1Therapeutics
01/2008
1Lasers (Laser)
01/2007